After meeting at a nightclub in a Mediterranean resort, seven young adults decide to continue partying aboard a luxury yacht in the middle of the ocean. But when one of them dies in a freak accident, the others argue about what to do, which leads to a ruthless fight for survival.

When this year's round of unsuspecting Northerners fail to show up for their annual Guts N' Glory Jamboree, the residents of Pleasant Valley take their cannibalistic carnival on the road and head to Iowa where they encounter spoiled heiresses Rome & Tina Sheraton and the cast and crew of their "Road Rascals" reality show. Performing "The Bloodiest Show on Earth", our Southern Maniacs prove more than ratings killers.

A team consisting of a physicist, his wife, a young female psychic and the only survivor of the previous visit are sent to the notorious Hell House to prove/disprove survival after death. Previous visitors have either been killed or gone mad, and it is up to the team to survive a full week in isolation, and solve the mystery of the Hell House.