The allure of easy money sends Mary Mason, a medical student, into the world of underground surgeries which ends up leaving more marks on her than her so called 'freakish' clients.

Inspector Tellini investigates serial crimes where victims are paralyzed while having their bellies ripped open with a sharp knife, much in the same way tarantulas are killed by the black wasp. As suspects keep dying, Inspector directs his attention to a spa all the victims had a connection with.

In Los Angeles, Jaron "Jizz" is a needy teenager that was molested when he was a child and works publishing advertisements for the sex industry. He discounts one hundred dollars in his paychecks to release Tara, who works in a peep-show in Paulie's, for the powerful lord of the sex industry Jimmy Sours. He teams-up with the whore Balery, who is seeking out a partner to steal from a rich client, to raise the necessary money to pay Jimmy. Mr. Garrett is the perverted Health teacher of a high-school; his sluttish students Melody and Courtney like to tease him, crossing their legs while wearing mini-skirts to see him masturbating in his car. Mr. Garrett takes them to join the Internet porn industry and to use pills, and Melody is raped by the sick teacher. The escort Chantel attends kinky clients to satisfy their fantasies and is protected by her pimp Wes. When Wes tries to force the entry in a client's house, the man reacts and the lives of the lead characters are entwined in a tragedy.