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Wes Block is a detective who's put on the case of a serial killer whose victims are young and pretty women, that he rapes and murders. The killings are getting personal when the killer chooses victims who are acquaintances of Block. Even his daughters are threatened.

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When two trash-picking boys from Rio's slums find a wallet in amongst the daily detritus of their local dump, little do they imagine that their lives are about to change forever. But when the local police show up, offering a handsome reward for the wallet's return, the boys, Rafael and Gardo, realize that what they've found must be important.

A wealthy harridan, Violet Venable, attempts to bribe Dr. Cukrowicz, a young psycho-surgeon from a New Orleans mental hospital that is desperately in need of funds, into lobotomizing her niece, Catherine Holly. Violet wants the operation performed in order to prevent Catherine from defiling the memory of her son, the poet Sebastian. Catherine has been babbling obscenely about Sebastian's mysterious death that she witnessed while on holiday together in Spain the previous summer.

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Col. Cord McNally an ex union officer teams up with a couple of ex Johnny Rebs to search for the traitor who sold information to the South during the Civil War. Their quest brings them to the town of Rio Lobo where they help recover this little Texas town from ruthless outlaws who are led by the traitor they were looking for.

Set in the south of the United States just after the Civil War, Laurel Sommersby is just managing to work the farm without her husband Jack, believed killed in the Civil War. By all accounts, Jack Sommersby was not a pleasant man, thus when he returns, Laurel has mixed emotions. It appears that Jack has changed a great deal, leading some people to believe that this is not actually Jack but an impostor. Laurel herself is unsure, but willing to take the man into her home, and perhaps later into her heart...

Sinister characters converge around a young man devoted to protecting those he loves in a postwar backwoods town teeming with corruption and brutality.